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2007;293:L972L981

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96 Tumor-inducing EGFR signaling induces the phosphorylation of phosphoglycerate kinase 1 (PGK1) at S256 by casein kinase 2 (CK2), leading to the binding of phosphorylated PGK1 to CDC7, converting local adenosine diphosphate produced by CDC7 into ATP, facilitating the recruitment of DNA helicase to the replication origin, and promoting DNA replication