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International Journal of Endocrinology, 2013 , 942030

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Gut Microbiome Modulation in Diet-Induced Obesity (PubMed, 2022) 5-Amino-1MQ Establishes a Distinct Microbiome Profile in DIO Mice A study published on PubMed investigated the effects of 5-Amino-1MQ combined with a low-fat diet on the gut microbiome of diet-induced obese mice

187 A study also shows that purpurin and its analog, R162, acting as mixed model inhibitors of GDH1, inhibit GDH1 activity, elevate ROS levels and thus attenuate cancer cell proliferation