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Physiological redox signaling operates within defined spatial and temporal limits, whereas sustained ROS overproduction overwhelms antioxidant buffering systems and causes lipid peroxidation, protein carbonylation, DNA damage, and neuronal dysfunction
[DOI] [PubMed] [Google Scholar] 2.OShea RS, Dasarathy S, McCullough AJ
Poor sterility during multi-use access
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Henan Med Res
The VEGFR2-Akt-eNOS signaling pathway was directly activated (i.e., without the need for other known ligands or shear stress), controlling vasomotor tone (both smooth muscle and endothelium), and the Src-Caveolin-1-eNOS pathway was activated [103,104]
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