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The FDA-approved starting dose for Ozempic and Wegovy is 0.25mg weekly, with therapeutic doses ranging from 0.5mg to 2.4mg
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The first drug in this class of medications was approved more than two decades ago to treat type 2 diabetes, but GLP-1s didnt explode in popularity until 2021
Retatrutide (LY3437943) is an investigational triple GLP-1, GIP, and glucagon receptor agonist developed by Eli Lilly, with Phase 2 clinical data published in 2023 showing dose-dependent body weight reductions and HbA1c improvements
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